Genetic regulation of pristane-induced oil granuloma responses

Pristane-Induced Lupus Oil Pristane: Implications for Induction of Apoptosis by the Hydrocarbon

Oil granuloma (paraffinoma) of the lung.

Regulation of Leukocyte Recruitment to the Spleen and Peritoneal Cavity during Pristane-Induced Inflammation

Chronic inflammation is associated with an increased number of leukocytes in the spleen, which are then redirected to the site of inflammation. However, it remains unknown how leukocyte recruitment is regulated. Herein, chronic inflammation was induced by intraperitoneal injection of pristane into mice. Leukocytes in the spleen or in the peritoneal cavity were quantified by flow cytometry. We f...

Maintenance of autoantibody production in pristane-induced murine lupus

BACKGROUND Pristane-treated mice chronically produce high levels of anti-ribonucleoprotein/Smith (anti-Sm/RNP) and other lupus autoantibodies. The present study addressed how these autoantibody levels are maintained over time. METHODS Lupus was induced in BALB/c mice using pristane. Naïve B cells, switched memory B cells, switched plasmablasts, and plasma cells were flow-sorted and total IgG ...

Characteristics of A - MuLV - Plus - Pristane - induced Plasmacytomas

The cells from plasmacytomas induced in BALB/c and susceptible BALB/c congenic strains of mice by pristane (2,6,10,14-tetramethylpentadecane) (1) have non-random chromosomal translocations, rcpt (6;15) or rcpt(12;15) (2, 3). To date, the karyotypes of 27 early transfer generation or primary pristine-induced plasmacytomas have determined, and 26 of the tumors have either rcpt(6; 15) or rcpt(12;1...